Metabolic Synchronization™: Getting Your Biology Back in Sync

Ever feel like your body’s working against you? Energy dips, cravings and excess weight that won’t budge — even though you’re trying everything. 

You’re not alone. More than 90% of U.S. adults are metabolically unhealthy^*, often without even knowing it. 

What feels like “everyday struggles” are actually alerts: signs your metabolism, your body’s engine, is out of sync. 

The good news is new research of the data found in a clinical study led by our scientific and clinical affairs team shows it’s possible to get your body working for you again. 

Science Is Driving a New Era in Metabolic Health

For decades, our comprehensive system has helped millions achieve quality weight loss through science-backed nutrition, coaching and habit creation. 

As metabolic dysfunction grew more rampant, our team dug deeper into how quality weight loss impacts metabolic health — analyzing clinical studies and thousands of datapoints to better understand how our 5 & 1 plan approach impacts the body’s metabolic health. 

The latest science shows the key is not how much weight you lose — it’s the type of weight. And that difference is the key to helping people unlock a body that works better over time. 

Metabolic Synchronization™

Introducing Metabolic Synchronization, our breakthrough science that reverses metabolic dysfunction, starting with a with a targeted reset. 

By improving body composition through a strong and targeted fat burn, Metabolic Synchronization works from the inside out. 

• Reduces up to 14% visceral fat** — targeting the bad fat that surrounds muscle and organs, interfering with how your body functions

• Retains 98% lean mass** — protecting healthy tissue for strength, mobility and more

• Supports healthy muscle — promoting your body’s ability to support an active metabolism — from efficient energy use to helping regulate body weight 

The result? Harmonization of key metabolic functions at the cellular level works from the inside out. The key is to shift body composition toward a body that looks better, feels better and functions at its best.  

Quality weight loss goes beyond the scale to target bad visceral fat while preserving lean mass and protecting healthy muscle — the very tissue that powers your metabolism, fuels energy use and keeps you strong. 

Built on Proven Science

Our comprehensive system is the result of decades of experience, 30+ research studies and currently motivates  an unwavering commitment to advancing metabolic health through science and support. 

When your body resets, everything starts to click. Energy improves. Sleep deepens. Mindset strengthens. Healthy habits start stacking — one simple choice leading to the next. 

The power of Metabolic Synchronization is its ability to get your body working FOR you, not against you. 

Support Compounds Success

When science meets human connection, results multiply. 

96% of Americans recognize that lifestyle changes are essential for weight loss and management — yet only 17% feel confident they can go it alone.^† 

That’s where the coach comes in. 

Coaches help clients translate science into action — turning structure into daily rhythm, accountability into consistency and belief into progress. 

And that partnership pays off: 

• Up to 10x more weight loss^‡ 

• Up to 17x more fat loss^‡ 

Coaches turn data into direction, helping clients navigate their journey with accountability, empathy and real-world guidance. Community turns structure into strength — a shared rhythm of encouragement, progress and celebration that keeps momentum alive. 

Because transformation doesn’t happen in isolation. It happens through connection — one conversation, one habit, one day at a time. And when 50% of our daily actions are habits^§, this type of influence can make all the difference.  

The Future of Health Starts Here

When your body's in sync, your health — and your life — begin to move forward in harmony. 

Metabolic Synchronization™ starts with quality weight loss, and we’ve got a comprehensive system for just that.

By reducing fat, retaining lean mass and protecting muscle, it sparks metabolic transformation and helps you live in sync with your healthiest self. 

This discovery, announced in our recent press release, highlights how our science-backed system helps realign metabolism and improve body composition for long-term health. 

Learn more 

*O'Hearn M et al. Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018. J Am Coll Cardiol. 2022;80(2):138-151. doi: 10.1016/j.jacc.2022.04.046 

**Arterburn et al., 2019. In a clinical study, 98% of lean mass was retained on the Optimal Weight 5 & 1 Plan® at 16 weeks. In a clinical study, individuals on the OPTAVIA 5 & 1 Plan experienced a reduction of 14% adiposity visceral [visceral fat] at 16 weeks Arterburn LM, et al. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. 2018;5(1):3-14. doi: 10.1002/osp4.312. 

†Source: Independent IPSOS research commissioned by OPTAVIA, June 2023. 

^‡Those on the Optimal Weight 5&1 Plan® with support of an OPTAVIA coach™ successfully lost 10x more weight and 17x more fat than those who tried to lose weight on their own. Arterburn LM, Colman CD, Kiel J, Kelley K, Matilla L, Frye N, Sanoshy K, Cook CM. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. 

^§Andersen, Wayne Scott. Dr. A’s Habits of Health: The Path to Permanent Weight Control, Optimal Health, and Wellbeing. Habits of Health Press, 2019.